Latest publications

Discovery and validation of 2-styryl substituted benzoxazin-4-ones as a novel scaffold for rhomboid protease inhibitors
Bioorganic and Medicinal Chemistry Letters 28 (8): 1417-1422 (2018)
Benzoxazin-4-ones as novel, easily accessible inhibitors for rhomboid proteases
Bioorganic and Medicinal Chemistry Letters 28 (8): 1423-1427 (2018)
The Rhomboid Superfamily: Structural Mechanisms and Chemical Biology Opportunities
Trends in Biochemical Sciences 43 (9): 726-739 (2018)
Discovery and Biological Evaluation of Potent and Selective N-Methylene Saccharin-Derived Inhibitors for Rhomboid Intramembrane Proteases
Biochemistry 56 (51): 6713-6725 (2017)