Latest publications

Design, Synthesis, and Biochemical and Biological Evaluation of Novel 7-Deazapurine Cyclic Dinucleotide Analogues as STING Receptor Agonists
Journal of Medicinal Chemistry 65 (20): 14082–14103 (2022)
5′-Phosphonate modified oligoadenylates as potent activators of human RNase L
Bioorganic and Medicinal Chemistry 56: 116632 (2022)
Enzymatic Synthesis of 3′–5′, 3′–5′ Cyclic Dinucleotides, Their Binding Properties to the Stimulator of Interferon Genes Adaptor Protein, and Structure/Activity Correlations
Biochemistry 60 (48): 3714–3727 (2021)
Protein–Ligand Interactions in the STING Binding Site Probed by Rationally Designed Single-Point Mutations: Experiment and Theory
Biochemistry 60 (8): 607–620 (2021)