Scientific position

Postdoctoral position in medicinal chemistry of nucleoside analogues

Michal Hocek Group
Bioorganic and Medicinal Chemistry of Nucleic Acids

Job description

A fully funded postdoc position is available in Prof. Michal Hocek Group. The candidate will join a small international team within a large multidisciplinary group of the Joint Laboratory of Bioorganic and Medicinal Chemistry of Nucleic Acids of IOCB Prague and the Charles University in Prague. The project will involve the design and synthesis of novel modified nucleoside and nucleotide analogues for biological activity screening and applications in medicinal chemistry and chemical biology.


  • PhD degree in organic or medicinal chemistry
  • Well established experience and profound knowledge of synthetic organic chemistry
  • Additional experience in drug design and medicinal chemistry would be a plus
  • Ability to independently work on the research project
  • Good proficiency in spoken and written English

We offer

  • Competitive financial remuneration
  • Full-time fixed-term contract for 2 years
  • 5 weeks of vacation plus 3 sick days
  • Health insurance and full benefits package incl. contribution to supplementary pension insurance and contribution to sports/culture/leisure time
  • Meals subsidy
  • Financial support for mothers with young children
  • Located in the stunning city of Prague, our research facilities feature a state-of-the-art instrumentation portfolio

Additional information


The position is available as of September 1, 2022 or as soon as possible thereafter


The position is available for the period of 2 years


Applications will be reviewed and considered until the position is filled.

How to apply

Please submit cover letter, CV, list of publications and 2 reference letters by e-mail to Prof. Michal and to Dr. Michal Tichý:

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