Latest publications

Polysubstituted Pyrimidines as Potent Inhibitors of Prostaglandin E2 Production: Increasing Their Aqueous Solubility
ChemMedChem 2021: Early View
Development of Scalable Synthesis of 5-Butyl-4-(4-methoxyphenyl)-6-phenylpyrimidin-2-amine (WQE-134), a Dual Inhibitor of Nitric Oxide and Prostaglandin E2 Production
Organic Process Research & Development 24 (9): 1718-1724 (2020)
Polysubstituted Pyrimidines as mPGES‐1 Inhibitors: Discovery of Potent Inhibitors of PGE2 Production with Strong Anti‐inflammatory Effects in Carrageenan‐Induced Rat Paw Edema
ChemMedChem 15 (15): 1398-1407 (2020)
Influence of the C-5 substitution in polysubstituted pyrimidines on inhibition of prostaglandin E2 production
European Journal of Medicinal Chemistry 156 (5): 295-301 (2018)