Call for applications: Junior Group Leader position in organic synthesis
22 February 2021
IOCB Prague invites applications for a Junior Group Leader position in synthetic organic chemistry with a strong emphasis on synthetic approaches to complex target molecules at…
Understanding the origins of G-quadruplex biochemical specificity
17 February 2021
Guanine-rich nucleic acid sequences can form secondary structures called G-quadruplexes. These are composed of square planar guanine tetrads stacked on top of one other and…
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Stuffed pumpkins: mechanochemical synthesis of host–guest complexes with cucurbituril
Chemical Communications 2021: Early View
Solvent-free mechanochemical synthesis (ball-milling) was used to prepare inclusion complexes with cucurbituril and four model guest molecules (adamantane, adamantyl-1-amine hydrochloride, toluidine hydrochloride, and p-phenylenediamine dihydrochloride). Successful formation of individual inclusions was independently confirmed by one- and two-dimensional solid-state NMR techniques and differential scanning calorimetry. Mechanochemical synthesis represents an alternative path towards new types of cucurbit[n]uril/guest inclusion complexes that are not accessible due to limited solubility of the individual components.
Synthesis of N-perfluoroalkyl-3,4-disubstituted pyrroles by rhodium-catalyzed transannulation of N-fluoroalkyl-1,2,3-triazoles with terminal alkynes
Beilstein Journal of Organic Chemistry 17: 504–510 (2021)
Triazole fungicides in soil affect the yield of fruit, green biomass, and phenolics production of Solanum lycopersicum L.
Food Chemistry 2021: Early View
Iodination of CART(61‐102) peptide: Preserved binding and anorexigenic activity in mice
Journal of Labelled Compounds and Radiopharmaceuticals 64 (2): 61-64 (2021)