Scientific position

Postdoctoral position in medicinal chemistry

Radim Nencka Group
Drug Design and Medicinal Chemistry

Job description

A postdoctoral position in the senior research group Drug Design and Medicinal Chemistry headed by Dr. Radim Nencka is available for a highly motivated and creative scientist with expertise in organic and medicinal chemistry to participate in the project New Technologies for Translational Research in Pharmaceutical Sciences / NETPHARM, project ID CZ.02.01.01/00/22_008/0004607, which is co-funded by the European Union.

Our projects are at the forefront of identifying novel kinase and methyltransferase inhibitors as potential treatment for cancer and autoimmune diseases, aiming to make a significant impact in these critical areas of healthcare.

The successful candidate will work at IOCB Prague, a top European institution with state-of-the-art facilities for organic and medicinal chemistry, as well as biochemistry and molecular biology. The city of Prague offers a stimulating atmosphere and is an excellent place to live.


  • Ph.D. degree in Organic, Medicinal Chemistry, or a related field
  • Excellent expertise in organic synthesis and retrosynthetic analysis
  • Strong oral and written communication skills in English (proficiency equivalent to a standardized test such as TOEFL or IELTS)
  • Laboratory experience in organic synthesis
  • Prior experience with biochemical assays such as fluorescence anisotropy and surface plasmon resonance is advantageous
  • Experience in programming, working with Linux, and familiarity with CADD techniques would be considered advantageous

We offer

  • Work in a young and progressive scientific team of medicinal chemists, structural biologists, virologists, computational chemists, and biochemists
  • Competitive financial remuneration
  • 5 weeks of paid vacation plus 4 days of personal leave
  • Health insurance and a full benefits package including a contribution to supplementary pension insurance and support for sports, culture, and leisure activities
  • Meal subsidy
  • Financial support for parents with young children
  • Access to a state-of-the-art instrumentation portfolio
  • Life in the beautiful city of Prague

Additional information

Starting date

July-September 2024


Initial full-time fixed-term contract for one year, with the possibility of extension

How to apply

Please send a cover letter highlighting your competence and experience with respect to the requirements of this position, along with your CV, copy of PhD certificate, list of publications and contact information for two referees to Dr. Radim Nencka at the following e-mail address: by 15 June 2024.

Suitable candidates will be contacted to arrange an interview. Please note that if you are not contacted within 3 weeks, we have given preference to candidates who more closely meet the criteria. Thank you for your understanding.

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