IOCB covers 2018
Here are some of the front/back/inside covers created to accompany and illustrate the scientific articles authored by IOCB researchers and published in 2018.
Transport of nucleoside triphosphates into cells by artificial molecular transporters
Transport of nucleoside triphosphates across cell membranes does not proceed under ambient conditions. In their Communication on page 9891 ff., T. Kraus et al. show rapid and selective transport of various fluorescently labeled nucleoside triphosphates (NTPs) into eukaryotic and prokaryotic cells by artificial transporters. The labeled NTPs, which are instantly released in the intracellular space, can be exploited for tracing metabolic processes such as DNA synthesis in live cells. (Cover art: Tomáš Belloň / IOCB Prague)
- Article: Zawada, Z.; Tatar, A.; Mocilac, P.; Buděšínský, M.; Kraus, T. Transport of Nucleoside Triphosphates into Cells by Artificial Molecular Transporters. Angew. Chem. Int. Ed. 2018, 57, 9891–9895. https://doi.org/10.1002/anie.201801306
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Synthesis of dihydroxyalkynyl and dihydroxyalkyl nucleotides as building blocks or precursors for introduction of diol or aldehyde groups to DNA for bioconjugations
A facile approach has been developed for enzymatic synthesis of DNA modified by reactive aldehyde groups which can be used for post-synthetic decoration of DNA through bioconjugations with peptides or other molecules.
- Article: Krömer, M.; Bártová, K.; Raindlová, V.; Hocek, M. Synthesis of Dihydroxyalkynyl and Dihydroxyalkyl Nucleotides as Building Blocks or Precursors for Introduction of Diol or Aldehyde Groups to DNA for Bioconjugations. Chem. Eur. J. 2018, 24, 11890–11894. https://doi.org/10.1002/chem.201802282
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Protected 2′-deoxyribonucleoside triphosphate building blocks for the photocaging of epigenetic 5-(hydroxymethyl)cytosine in DNA
Cover art: Tomáš Belloň / IOCB Prague
- Article: Boháčová, S.; Vaníková, Z.; Poštová Slavětínská, L.; Hocek, M. Protected 2′-deoxyribonucleoside triphosphate building blocks for the photocaging of epigenetic 5-(hydroxymethyl)cytosine in DNA. Org. Biomol. Chem. 2018, 16, 5427–5432. https://doi.org/10.1039/C8OB01106K
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Special Issue: Institute Feature: IOCB Prague
The Front Cover shows the newly constructed organic synthesis building of the IOCB Prague. Featuring at the front are examples of molecules that are showcased in this collection of papers from researchers of the IOCB. (Cover art: Tomáš Belloň / IOCB Prague)
Dihydrogen contacts observed by through-space indirect NMR coupling
Cover art: Tomáš Belloň / IOCB Prague
- Article: Dračínský, M.; Buchta, M.; Buděšínský, M.; Vacek-Chocholoušová, J.; Stará, I. G.; Starý, I.; Malkina, O. L. Dihydrogen contacts observed by through-space indirect NMR coupling. Chem. Sci. 2018, 9, 7437–7446. https://doi.org/10.1039/C8SC02859A
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Nonhydroxylated 1-O-acylceramides in vernix caseosa
Article: Harazim, E.; Vrkoslav, V.; Buděšínský, M.; Harazim, P.; Svoboda, M.; Plavka, R.; Bosáková, Z.; Cvačka, J. Nonhydroxylated 1-O-acylceramides in vernix caseosa. J. Lipid Res. 2018, 59, 2164–2173. https://doi.org/10.1194/jlr.M088864
The matrix-assisted laser desorption/ionisation in-source decay of peptides using ion mobility enabled quadrupole-time-of-flight mass spectrometry
Covert art: Tomáš Belloň / IOCB Prague
- Article: Vrkoslav, V.; Muck, A.; Brown, J. M.; Hubálek, M.; Cvačka, J. The matrix-assisted laser desorption/ionisation in-source decay of peptides using ion mobility enabled quadrupole-time-of-flight mass spectrometry. Rapid Commun. Mass Spectrom. 2018, 32, 2099–2105. https://doi.org/10.1002/rcm.8284
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