Hugo Kocek

All publications

Latest publications

First-in-Class Inhibitors of the Protein Lysine Methyltransferase METTL21A

H. Kocek M. Vaško M. Dejmek E. Procházková M. Šála A. Janovská M. Matoušová A. Dvořáková E. Bouřa R. Nencka

European Journal of Medicinal Chemistry 319: 119227 (2026)

Iodine-Mediated On-DNA Oxidative Cyclization of 2-Pyridylhydrazones for 1,2,4-Triazolo[4,3-a]pyridines

S. W. Hong T. E. Kim J. Lee H. Kocek G. T. Hwang M. Song

Organic Letters 28 (28): 8878–8883 (2026)

Chiroptical spectroscopy complemented by quantum chemical calculations accurately predicts the absolute configuration of P-chirogenic compounds

M. Pazderková F. Králík H. Kocek M. Christou Tichotová L. Tučková L. Bednárová E. Procházková

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 330: 125674 (2025)

Discovery of highly potent SARS-CoV-2 nsp14 methyltransferase inhibitors based on adenosine 5′-carboxamides

H. Kocek D. Chalupská A. Dvořáková M. Zgarbová M. Šála K. Chalupský P. Krafčíková T. Otava M. Drexler E. Procházková B. Klepetářová M. Štefek J. Kozic H. Mertlíková-Kaiserová E. Bouřa J. Weber R. Nencka

RSC Medicinal Chemistry 15 (10): 3469-3476 (2024)