Lucie Svobodová

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Latest publications

Targeting NFE2L1 signalling with small molecules to protect against Ferroptosis

L. Svobodová J. Sedláček Z. Šmahelová P. Majer A. Machara K. Grantz Šašková

Bioorganic and Medicinal Chemistry Letters 130: 130425 (2026)

Investigating NFE2L1 activators for targeted protein aggregate clearance: a follow-up study

Z. Šmahelová L. Svobodová J. Sedláček M. Adámek M. Pimková Polidarová P. Majer A. Machara K. Grantz Šašková

RSC Medicinal Chemistry 16 (12): 6397–6411 (2025)

Small-molecule activators of NRF1 transcriptional activity prevent protein aggregation

J. Sedláček Z. Šmahelová M. Adámek D. Šubová L. Svobodová A. Kadlecová P. Majer A. Machara K. Grantz Šašková

Biomedicine & Pharmacotherapy 183: 117864 (2025)