Irena Selicharová

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Latest publications

Combinatorial libraries of bipodal binders of the insulin receptor

I. Selicharová B. Fabre M. S. Garre Hernandez M. Lubos J. Pícha Z. Voburka K. Mitrová J. Jiráček

ChemMedChem 19 (11): e202400145 (2024)

Insulin receptor Arg717 and IGF-1 receptor Arg704 play a key role in ligand binding and in receptor activation

A. Kertisová L. Žáková K. Macháčková A. Marek P. Šácha P. Pompach J. Jiráček I. Selicharová

Open Biology 13 (11): 230142 (2023)

Non-glycosylated IGF2 prohormones are more mitogenic than native IGF2

P. Potalitsyn L. Mrázková I. Selicharová M. Tencerová M. Ferenčáková M. Chrudinová T. Turnovská A. M. Brzozowski A. Marek J. Kaminský J. Jiráček L. Žáková

Communications Biology 6: 863 (2023)

Mutations at hypothetical binding site 2 in insulin and insulin-like growth factors 1 and 2

J. Jiráček I. Selicharová L. Žáková

Hormone Receptors: Structures and Functions, Vitamins and Hormones Vol. 123 (G. Litwack, Ed.), 187-230, Elsevier (2023)