Irena Selicharová

All publications

Latest publications

An engineered insulin analog with dual insulin and IGF-1 receptor agonism and distinct signaling

I. Selicharová N. S. Kirk A. Kertisová M. Lubos K. Mitrová T. Ticháčková L. Žáková M. Chrudinová J. Březinová K. Harant J. Voldřich M. Hájek D. M. Huffman J. Jiráček

Science Advances 12 (20): eaeb7558 (2026)

Conformational changes in insulin receptor illuminated by live-cell linear dichroism imaging and a FLIP biosensor

A. Sakhi A. Kertisová M. Lubos P. Miclea P. Khoroshyy T. Nešporová F. Filandr V. Nagy Marková I. Selicharová

Scientific Reports 16: 34502 (2026)

Expedient single-round selection of hyper-modified aptamer targeting insulin receptor from over-represented dually nucleobase-modified DNA libraries

P. A. Franco Urquijo M. Ondruš J. Kurfürst J. Škerlová I. Selicharová L. Mužíková Čechová H. Šváchová A. Semerádtová A. Filimoněnko A. Fejfarová J. Homola T. Kouba M. Hocek

Nature Communications 17: 6895 (2026)

Vesiculin reveals the role of the IGF2 C-domain in receptor specificity within the insulin–IGF system

K. Mrzílková M. Lubos K. Hladoníková I. Selicharová J. Jiráček J. Kaminský L. Žáková

Protein Science 35 (6): e70606 (2026)