CS
Pavel Šácha

Pavel Šácha

mail pavel.sachainvalid-email-name@invalid-email-domainuochb.cas.cz
phone +420 220 183 452
Group leader
IOCB Compound Library
Pavel Šácha Group
Scientist
Jan Konvalinka Group
Proteases of Human Pathogens
All publications

Latest publications

The Development of a High-Affinity Conformation-Sensitive Antibody Mimetic Using a Biocompatible Copolymer Carrier (iBody)
K. Blažková J. Beranová M. Hradilek L. Kostka V. Šubr T. Etrych P. Šácha J. Konvalinka
Journal of Biological Chemistry 297 (5): 101342 (2021)
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Structure-activity relationship and biochemical evaluation of novel fibroblast activation protein and prolyl endopeptidase inhibitors with α-ketoamide warheads
A. Šimková T. Ormsby N. Sidej L. Poštová Slavětínská J. Brynda J. Beranová P. Šácha P. Majer J. Konvalinka
European Journal of Medicinal Chemistry 224: 113717 (2021)
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Re-emerging Aspartic Protease Targets: Examining Cryptococcus neoformans Major Aspartyl Peptidase 1 as a Target for Antifungal Drug Discovery
R. Kryštůfek P. Šácha J. Starková J. Brynda M. Hradilek E. Tloušťová J. Grzymska W. Rut M. J. Boucher M. Drag P. Majer M. Hájek P. Řezáčová H. D. Madhani C. S. Craik J. Konvalinka
Journal of Medicinal Chemistry 64 (10): 6706–6719 (2021)
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The efficiency of insulin production and its content in insulin-expressing model β-cells correlate with their Zn2+ levels
P. Dzianová S. Asai M. Chrudinová L. Kosinová P. Potalitsyn P. Šácha R. Hadravová I. Selicharová J. Kříž J. P. Turkenburg A. M. Brzozowski J. Jiráček L. Žáková
Open Biology 10 (10): 200137 (2020)
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