CS
Pavel Šácha

Pavel Šácha

mail pavel.sachainvalid-email-name@invalid-email-domainuochb.cas.cz
phone +420 220 183 452
Group leader
IOCB Compound Library
Pavel Šácha Group
Scientist
Jan Konvalinka Group
Proteases of Human Pathogens
All publications

Latest publications

The Development of a High-Affinity Conformation-Sensitive Antibody Mimetic Using a Biocompatible Copolymer Carrier (iBody)
K. Blažková J. Beranová M. Hradilek L. Kostka V. Šubr T. Etrych P. Šácha J. Konvalinka
Journal of Biological Chemistry 297 (5): 101342 (2021)
Go to the publication arrow
The role of the biotin linker in polymer antibody mimetics, iBodies, in biochemical assays
V. Šubr T. Ormsby P. Šácha J. Konvalinka T. Etrych L. Kostka
Polymer Chemistry 12 (41): 6009-6021 (2021)
Go to the publication arrow
Structure-activity relationship and biochemical evaluation of novel fibroblast activation protein and prolyl endopeptidase inhibitors with α-ketoamide warheads
A. Šimková T. Ormsby N. Sidej L. Poštová Slavětínská J. Brynda J. Beranová P. Šácha P. Majer J. Konvalinka
European Journal of Medicinal Chemistry 224: 113717 (2021)
Go to the publication arrow
Re-emerging Aspartic Protease Targets: Examining Cryptococcus neoformans Major Aspartyl Peptidase 1 as a Target for Antifungal Drug Discovery
R. Kryštůfek P. Šácha J. Starková J. Brynda M. Hradilek E. Tloušťová J. Grzymska W. Rut M. J. Boucher M. Drag P. Majer M. Hájek P. Řezáčová H. D. Madhani C. S. Craik J. Konvalinka
Journal of Medicinal Chemistry 64 (10): 6706–6719 (2021)
Go to the publication arrow