Pavel Šácha

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Latest publications

Efficient Method for High-Throughput Screening of Compound Libraries Targeting Human PD-L1

M. R. Zamani K. Čermáková M. Hadzima P. Šácha J. Konvalinka

ACS Omega 11 (13): 20626–20635 (2026)

Potent Competitive Inhibitors of Ecto-5′-nucleotidase (CD73) based on 6-(Het)aryl-7-deazapurine Ribonucleoside 5′-O-Bisphosphonates

U. Šinkevičiüté M. Šímová R. Staník L. Poštová Slavětínská K. Blažková P. Šácha M. Lepšík J. Řezáč J. Konvalinka T. Ormsby M. Tichý M. Hocek

ACS Pharmacology & Translational Science 9 (1): 191–213 (2026)

Uncovering the glutamate carboxypeptidase II microenvironment using a multi-labeling proteomic approach

J. Pokorná M. Hadzima A. Křenková J. D. Smith V. Šubr R. Kryštůfek M. Hubálek J. Starková K. Šrámková T. Etrych L. Kostka F. Sedlák J. Konvalinka P. Šácha

Scientific Reports 15: 45461 (2025)

MSⁿLib: efficient generation of open multi-stage fragmentation mass spectral libraries

C. Brungs R. Schmid S. Heuckeroth A. Mazumdar M. Drexler P. Šácha P. C. Dorrestein D. Petras L. Nothias V. Veverka R. Nencka Z. Kameník T. Pluskal

Nature Methods 22: 2028–2031 (2025)