+420 220 183 273
2001-2004
Ph.D., Organic Chemistry, Charles University’s Faculty of Science, Prague, Czech Republic
Thesis: Synthesis of Neurosteroids: Modulators of NMDA Receptor
1999-2004
M.Sc., Organic Chemistry, Charles University’s Faculty of Science, Prague, Czech Republic
Diploma work: Synthesis and stability of derivatives of 7-hydroxyepiandrosterone
Eva Kudová, Ph.D.
Profile
Education
Appointments
2022-present
Junior Research Group Leader - Neurosteroids, Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Prague
2012-2022
Targeted Research Group Leaders - Steroidal Inhibitors, Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Prague
July 2011-December 2011 (6 months)
PostDoctoral Fellow, Department of Medicinal Steroids, Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Prague
2009-2011 (2 years)
PostDoctoral Research Associate, Washington University in St. Louis School of Medicine, St. Louis, MO, USA
Mentor: Prof. Douglas. F. Covey
Research Focus: Synthesis of neurosteroids and their effects on GABAA receptor function
Research interests
Organic synthesis, medicinal chemistry, steroids, neurosteroids
Latest publications
Anti-Nociceptive Effects of Sphingomyelinase and Methyl-Beta-Cyclodextrin in the Icilin-Induced Mouse Pain Model
International Journal of Molecular Sciences 25 (9): 4637 (2024)
A zuranolone nanocrystal formulation enables solubility-independent in vivo study of pentylenetetrazol-induced seizures in a rat model
RSC Pharmaceutics 1 (1): 37-46 (2024)
C-3 Steroidal Hemiesters as Inhibitors of 17β-Hydroxysteroid Dehydrogenase Type 10
ACS Omega 9 (10): 12116–12124 (2024)
5β-reduced neuroactive steroids as modulators of growth and viability of postnatal neurons and glia
Journal of Steroid Biochemistry and Molecular Biology 239: 106464 (2024)