+420 220 183 273
2001-2004
Ph.D., Organic Chemistry, Charles University’s Faculty of Science, Prague, Czech Republic
Thesis: Synthesis of Neurosteroids: Modulators of NMDA Receptor
1999-2004
M.Sc., Organic Chemistry, Charles University’s Faculty of Science, Prague, Czech Republic
Diploma work: Synthesis and stability of derivatives of 7-hydroxyepiandrosterone
Eva Kudová, Ph.D.
Profile
Education
Appointments
2022-present
Junior Research Group Leader - Neurosteroids, Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Prague
2012-2022
Targeted Research Group Leaders - Steroidal Inhibitors, Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Prague
July 2011-December 2011 (6 months)
PostDoctoral Fellow, Department of Medicinal Steroids, Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Prague
2009-2011 (2 years)
PostDoctoral Research Associate, Washington University in St. Louis School of Medicine, St. Louis, MO, USA
Mentor: Prof. Douglas. F. Covey
Research Focus: Synthesis of neurosteroids and their effects on GABAA receptor function
Research interests
Organic synthesis, medicinal chemistry, steroids, neurosteroids
Latest publications
Steroidal hormones and neurosteroids - novel therapeutic strategies in bacterial infections: Design, synthesis, and biological evaluation
European Journal of Medicinal Chemistry 308: 118716 (2026)
Fluorescence-based assay for rapid screening of GABAA receptor modulating steroid antagonists (GAMSA)
Analytical Biochemistry 711: 116048 (2026)
Pregnanolone-Based Prodrugs as a Strategy for Neuroprotective Drug-Like Compounds: Pregnanolone Pyroglutamate and Its Age‑dependent Anticonvulsant Effects in the 6-hz Seizure Model in Immature Rats
Drug Design, Development and Therapy 20: 566239 (2026)
Pregnanolone Glutamate: A Dual-Fate Delivery System for Neuroactive Steroids in Perinatal Focal Cerebral Ischemia
International Journal of Molecular Sciences 27 (5): 2506 (2026)