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Tomáš Tichý

mail tomas.tichyinvalid-email-name@invalid-email-domainuochb.cas.cz
telefon +420 220 183 375
Scientist
Pavel Majer Group
Drug Discovery
All publications

Latest publications

Dendrimer-Conjugated Glutamine Antagonist, D-TTM020, Ameliorates Brain Immune Dysregulation and Improves Neurobehavioral Deficits in the Mecp2-Deficient Mouse Model
P. Vyas E. Smith Khoury N. Sah A. Sharma J. A. Labastida E. L. Wilkinson K. Lac N. N. L. Damiba A. Fowler J. Liu A. Bedner P. Majer T. Tichý A. G. Thomas R. Rais B. S. Slusher R. M. Kannan S. Kannan
Cells 15 (3): 272 (2026)
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Inhibition of microglial glutaminase alleviates chronic stress-induced neurobehavioral and cognitive deficits
M. Huang Y. Li A. Thomas A. Sharma W. Liyanage T. Tichý L. Tenora Y. Su J. Ha N. Hin M. Obayashi P. Majer R. M. Kannan T. Tsukamoto G. Ursini R. Rais B. S. Slusher X. Zhu
Neurotherapeutics 22 (6): e00759 (2025)
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Enhanced Oral Bioavailability of 2-(Phosphonomethyl)-pentanedioic Acid (2-PMPA) from its (5-Methyl-2-oxo-1,3-dioxol-4-yl)methyl (ODOL)-Based Prodrugs
R. P. Dash T. Tichý V. Veeravalli J. Lam J. Alt Y. Wu L. Tenora P. Majer B. S. Slusher R. Rais
Molecular Pharmaceutics 16 (10): 4292-4301 (2019)
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N-Substituted Prodrugs of Mebendazole Provide Improved Aqueous Solubility and Oral Bioavailability in Mice and Dogs
S. C. Zimmermann T. Tichý R. P. Dash C. E. Slusher A. J. Gadiano Y. Wu A. Jančařík L. Tenora L. Monincová E. Prchalová G. J. Riggins P. Majer B. S. Slusher R. Rais
Journal of Medicinal Chemistry 61 (9): 3918-3929 (2018)
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