CS
Petr Pachl

Petr Pachl

mail petr.pachlinvalid-email-name@invalid-email-domainuochb.cas.cz
phone +420 220 183 210
Postdoctoral fellow
Pavlína Maloy Řezáčová Group
Structural Biology
All publications

Latest publications

An evolutionary molecular adaptation of an unusual stefin from the liver fluke Fasciola hepatica redefines the cystatin superfamily
M. Buša Z. Matoušková P. Bartošová-Sojková P. Pachl P. Řezáčová R. M. Eichenberger P. Deplazes M. Horn S. Štefanic M. Mareš
Journal of Biological Chemistry 299 (3): 102970 (2023)
Go to the publication arrow
C1′-Branched acyclic nucleoside phosphonates mimicking adenosine monophosphate: Potent inhibitors of Trypanosoma brucei adenine phosphoribosyltransferase
F. Kalčic J. Frydrych E. Doleželová M. Slapničková P. Pachl L. Poštová Slavětínská M. Dračínský D. Hocková A. Zíková Z. Janeba
European Journal of Medicinal Chemistry 25: 113798 (2021)
Go to the publication arrow
Imidazo[1,2-c]pyrimidin-5(6H)-one inhibitors of CDK2: Synthesis, kinase inhibition and co-crystal structure
J. Jansa R. Jorda J. Škerlová P. Pachl M. Peřina E. Řezníčková T. Heger T. Gucký P. Maloy Řezáčová P. Řezáčová A. Lyčka V. Kryštof
European Journal of Medicinal Chemistry 216: 113309 (2021)
Go to the publication arrow
Azanitrile Inhibitors of the SmCB1 Protease Target Are Lethal to Schistosoma mansoni: Structural and Mechanistic Insights into Chemotype Reactivity
A. Jílková M. Horn J. Fanfrlík J. Küppers P. Pachl P. Řezáčová M. Lepšík P. Fajtová M. Chanová C. R. Caffrey M. Gütschow M. Mareš
ACS Infectious Diseases 7 (1): 189-201 (2021)
Go to the publication arrow