Petr Pachl

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Latest publications

Structural mechanism and inhibitor discovery for DhhP, a Borrelia burgdorferi cyclic di-AMP phosphodiesterase with an Fe/Mn bimetallic center

M. Klíma M. Dejmek A. Palusová D. Chalupská P. Pachl A. Hušková J. Hraníček K. Chalupský M. Moos R. Nencka J. Perner E. Bouřa

Structure 2026: Early View

N-Aryl-N-Lactosylamides as Potent and Highly Selective Inhibitors of Galectin-3 with Antifibrotic Activity Clic

J. Zýka J. Kozák L. Vaneková M. Pimková Polidarová V. Prouza N. Habanová T. Strmeň M. Zavřel P. Pachl J. Choutka K. Grantz Šašková A. Brázdová K. Parkan R. Pohl

Journal of Medicinal Chemistry 68 (22): 24624–24648 (2025)

Protein crystallization and structure determination at room temperature in the CrystalChip

P. Pachl L. Coudray R. Vincent L. Nilles H. Scheer C. Ritzenthaler A. Fejfarová P. Řezáčová S. Engilberge C. Sauter

FEBS Open Bio 15 (4): 532–541 (2025)

Structural analysis of the stable form of fibroblast growth factor 2 – FGF2-STAB

G. de La Bourdonnaye M. Marek T. Ghazalová J. Damborský P. Pachl J. Brynda V. Štěpánková R. Chaloupková

Journal of Structural Biology: X 10: 100112 (2024)