Jan Skácel, Ph.D.
Latest publications
Design, Synthesis, Biological Evaluation, and Crystallographic Study of Novel Purine Nucleoside Phosphorylase Inhibitors
Journal of Medicinal Chemistry 66 (10): 6652–6681 (2023)
Acyclic nucleoside phosphonates with 2-aminothiazole base as inhibitors of bacterial and mammalian adenylate cyclases
European Journal of Medicinal Chemistry 222: 113581 (2021)
Synthesis of Tetrasubstituted Thiophenes via Direct Metalation
Journal of Organic Chemistry 85 (2): 788-797 (2020)
Sulfide, sulfoxide and sulfone bridged acyclic nucleoside phosphonates as inhibitors of the Plasmodium falciparum and human 6-oxopurine phosphoribosyltransferases: Synthesis and evaluation
European Journal of Medicinal Chemistry 183: 111667 (2019)