+420 220 183 372
2003
Alfred Bader Prize for Organic Chemistry from the Czech Chemical Society
Tomáš Kraus, Ph.D.
Profile
Awards
Education
1988-1993
Undergraduate studies at the Charles University, Prague, M.Sc. degree (majoring in organic chemistry)
1993-2000
Ph.D. studies at Institute of Organic Chemistry and Biochemistry, Prague and Institute of Chemical Technology, Prague; (1/1999–7/2000 interrupted due to civil service)
Appointments
2002-2003
Postdoctoral studies with Jean-Pierre Sauvage, Université Louis Pasteur, Strasbourg; Individual Marie-Curie Fellowship
2007-2011
Leader of junior research group at Institute of Organic Chemistry and Biochemistry CAS, Prague
2012-2015
Leader of „Targeted research team“ at Institute of Organic Chemistry and Biochemistry CAS, Prague, focused on the development of delivery systems for nucleoside triphosphates.
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Latest publications
Zwitterionic DNA: enzymatic synthesis of hypermodified DNA bearing four different cationic substituents at all four nucleobases
Nucleic Acids Research 53 (5): gkaf155 (2025)
Real-time Imaging of Nascent DNA in Live Cells by Monitoring the Fluorescence Lifetime of DNA-Incorporated Thiazole Orange-Modified Nucleotides
Angewandte Chemie International Edition 62 (38): e202307548 (2023)
trans-Cyclooctene- and Bicyclononyne-Linked Nucleotides for Click Modification of DNA with Fluorogenic Tetrazines and Live Cell Metabolic Labeling and Imaging
Bioconjugate Chemistry 34 (4): 772–780 (2023)
Lipid-linked nucleoside triphosphates for enzymatic synthesis of hydrophobic oligonucleotides with enhanced membrane anchoring efficiency
Chemical Science 14 (15): 4059–4069 (2023)