Your web browser is out of date. Update your browser for more security, speed and the best experience on this site

Lanny S. Liebeskind

17 June 2009
IOCB Prague
Prof. Lanny S. Liebeskind (Emory University, Atlanta, GA, USA)
Seeking Novel Reactivity and High Selectivity in Modern Organic Synthesis: Studies of the pH-Neutral, Cu-Catalyzed Formation of Carbon-Carbon and Carbon-Heteroatom Bonds and their Application to Biomedically Relevant Synthesis


Achieving high chemoselectivity in functionally complex systems under mild reaction conditions is a significant 21st century challenge for synthetic scientists. In contrast to biological processes, where exquisite selectivity is achieved in vivo in functionally very complex systems through the fine-tuning of protein structure to function, achieving high chemoselectivity on functionally complex molecules in non-enzymatic systems in vitro requires alternative strategies of control. This lecture will describe new control strategies that have led to the development of novel synthetic methods for pH-neutral carbon-carbon and carbon-heteroatom bond formation from nominally unreactive bond types.
Share this article