Registration & producers: Dermazulen 1969 (Spofa / Zentiva)
Guaiazulene is a natural compound found in chamomile oil. It is known for its healing, anti-inflammatory, and mild disinfectant properties. It has also been used to treat skin damaged by radiotherapy. Large-scale chemical synthesis was developed at IOCB in the 1950s, and Dermazulen ointment was introduced to the market in 1969. František Šorm, the founder and first director of IOCB, made significant contributions to this research.
It remains a popular drug 50 years later.