Registration & producers: Dermazulen 1969 (Spofa / Zentiva)
Guaiazulene is a natural compound found in chamomile oil. It is known for its healing, anti-inflammatory, and mild disinfectant properties. It has also been used to treat skin damaged by radiotherapy. Large-scale chemical synthesis was developed at IOCB in the 1950s, and Dermazulen ointment was introduced to the market in 1969.
It remains a popular drug 50 years later. František Šorm, the founder and first director of IOCB, made significant contributions to this research.