Profile

Education
1996-2001
M.Sc. in Pharmacy, at Charles University in Prague, Faculty of Pharmacy in Hradec Králové (under supervision of Prof. Manolis Stratakis at University of Crete, Greece and Miroslav Miletín, Ph.D. at Charles University).
2001-2008
Ph.D. in Organic Chemistry at Department of Organic Chemistry, Charles University, Prague; (under supervision of Dr. H. Hřebabecký at Institute of Organic Chemistry and Biochemistry of the CAS).
Appointments
2009-2010
Postdoctoral Fellow at Laboratory of Medicinal Chemistry (Prof. Serge Van Calenbergh), Faculty of Pharmaceutical Sciences, University of Ghent, Ghent, Belgium. (Synthesis of nucleotide analogues as P2Y2 receptor ligands).
2001 (5 months)
Short stay at University of Crete, Heraklion, Greece.
Since 2010
Head of the Junior Research Team, Institute of Organic Chemistry and Biochemistry of the CAS.

Latest publications

Inhibitors of mpox VP39 2′-O methyltransferase efficiently inhibit the monkeypox virus
Antiviral Research 218: 105714 (2023)
Exploring positions 6 and 7 of a quinazoline-based scaffold leads to changes in selectivity and potency towards RIPK2/3 kinases
European Journal of Medicinal Chemistry 260: 115717 (2023)