M.Sc. in Pharmacy, at Charles University in Prague, Faculty of Pharmacy in Hradec Králové (under supervision of Prof. Manolis Stratakis at University of Crete, Greece and Miroslav Miletín, Ph.D. at Charles University).
Ph.D. in Organic Chemistry at Department of Organic Chemistry, Charles University, Prague; (under supervision of Dr. H. Hřebabecký at Institute of Organic Chemistry and Biochemistry of the CAS).
Postdoctoral Fellow at Laboratory of Medicinal Chemistry (Prof. Serge Van Calenbergh), Faculty of Pharmaceutical Sciences, University of Ghent, Ghent, Belgium. (Synthesis of nucleotide analogues as P2Y2 receptor ligands).
2001 (5 months)
Short stay at University of Crete, Heraklion, Greece.
Since 2010
Head of the Junior Research Team, Institute of Organic Chemistry and Biochemistry of the CAS.

Latest publications

Discovery and structural characterization of monkeypox virus methyltransferase VP39 inhibitors reveal similarities to SARS-CoV-2 nsp14 methyltransferase
Nature Communications 14: 2259 (2023)
SWI/SNF Blockade Disrupts PU.1-Directed Enhancer Programs in Normal Hematopoietic Cells and Acute Myeloid Leukemia
Cancer Research 83 (7): 983–996 (2023)
Discovery of Novel Human Constitutive Androstane Receptor Agonists with the Imidazo[1,2-a]pyridine Structure
Journal of Medicinal Chemistry 66 (4): 2422–2456 (2023)