M.Sc. in Pharmacy, at Charles University in Prague, Faculty of Pharmacy in Hradec Králové (under supervision of Prof. Manolis Stratakis at University of Crete, Greece and Miroslav Miletín, Ph.D. at Charles University).
Ph.D. in Organic Chemistry at Department of Organic Chemistry, Charles University, Prague; (under supervision of Dr. H. Hřebabecký at Institute of Organic Chemistry and Biochemistry of the CAS).
Postdoctoral Fellow at Laboratory of Medicinal Chemistry (Prof. Serge Van Calenbergh), Faculty of Pharmaceutical Sciences, University of Ghent, Ghent, Belgium. (Synthesis of nucleotide analogues as P2Y2 receptor ligands).
2001 (5 months)
Short stay at University of Crete, Heraklion, Greece.
Since 2010
Head of the Junior Research Team, Institute of Organic Chemistry and Biochemistry of the CAS.

Latest publications

Fluorinated cGAMP analogs, which act as STING agonists and are not cleavable by poxins: Structural basis of their function
Structure 2024: Early View
Design, synthesis and evaluation of novel thieno[2,3d]pyrimidine derivatives as potent and specific RIPK2 inhibitors
Bioorganic and Medicinal Chemistry Letters 97: 129567 (2024)
Inhibitors of mpox VP39 2′-O methyltransferase efficiently inhibit the monkeypox virus
Antiviral Research 218: 105714 (2023)