Radim Nencka, Ph.D.

Všechny publikace

Nejnovější publikace

Exploring advanced methodologies for NS5 methyltransferase targeted drug discovery

T. Otava M. Drexler P. Krafčíková K. Chalupský V. Veverka E. Bouřa R. Nencka

European Journal of Medicinal Chemistry 303: 118388 (2026)

Mechanistic insights into alcohol-induced DNA crosslink repair by Slx4-Xpf-Ercc1 nuclease complex in the Fanconi anaemia pathway

J. Havlíková M. Dejmek A. Hušková A. Allan E. Bouřa R. Nencka J. Šilhán

Communications Biology 8: 1374 (2025)

MSⁿLib: efficient generation of open multi-stage fragmentation mass spectral libraries

C. Brungs R. Schmid S. Heuckeroth A. Mazumdar M. Drexler P. Šácha P. C. Dorrestein D. Petras L. Nothias V. Veverka R. Nencka Z. Kameník T. Pluskal

Nature Methods 22: 2028–2031 (2025)

Discovery of PXR Antagonist MI891 and PXR Degrader MI1013 and Their Roles in Hepatic Gene Regulation

R. Kamaraj I. Mejdrová M. Krutáková T. Smutný K. Škach K. Dohnalová L. Smutná D. S. S. Nellore J. Dušek K. Chalupský J. Hricová T. Kronenberger A. Stahl M. Templin A. Braeuning R. Nencka P. Pávek

Journal of Medicinal Chemistry 68 (14): 14271–14299 (2025)