Radim Nencka, Ph.D.

Všechny publikace

Nejnovější publikace

Discovery of highly potent SARS-CoV-2 nsp14 methyltransferase inhibitors based on adenosine 5′-carboxamides

H. Kocek D. Chalupská A. Dvořáková M. Zgarbová M. Šála K. Chalupský P. Krafčíková T. Otava M. Drexler E. Procházková B. Klepetářová M. Štefek J. Kozic H. Mertlíková-Kaiserová E. Bouřa J. Weber R. Nencka

RSC Medicinal Chemistry 2024: Early View

Structure–activity relationship study of small-molecule inhibitor of Atg12-Atg3 protein–protein interaction

K. Škach J. Böserle G. C. Nuta P. Břehová S. Bialik N. Kozer H. Barr E. Chaloupecká A. Kimchi R. Nencka

Bioorganic and Medicinal Chemistry Letters 112: 129939 (2024)

Structure of SARS-CoV-2 MTase nsp14 with the inhibitor STM957 reveals inhibition mechanism that is shared with a poxviral MTase VP39

E. Žilecká M. Klíma M. Štefek M. Dejmek R. Nencka E. Bouřa

Journal of Structural Biology: X 10: 100109 (2024)

Application of established computational techniques to identify potential SARS-CoV-2 Nsp14-MTase inhibitors in low data regimes

A. K. Nigam M. F. D. Hurley F. Li E. Konkoľová M. Klíma J. Trylčová R. Pollice S. S. Çinaroǧlu R. Levin-Konigsberg J. Handjaya M. Schapira I. Chau S. Perveen H. Ng H. Ü. Kaniskan Y. Han S. Singh C. Gorgulla A. Kundaje J. Jin V. A. Voelz J. Weber R. Nencka E. Bouřa M. Vedadi A. Aspuru-Guzik

Digital Discovery 3 (7): 1327-1341 (2024)