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Ing. Lukáš Severa, Ph.D.

mail lukas.severainvalid-email-name@invalid-email-domainuochb.cas.cz
telefon +420 220 183 406
telefon +420 220 183 133
Postdoctoral fellow
Jiří Kaleta Group
Molecular Devices

Profile

EDUCATION

APPOINTMENTS

  • since 2019: Postdoctoral fellowship, IOCB Prague, Czech Republic, supervisor: Jiří Kaleta, Ph.D.

    • 2018: Postdoctoral fellowship, IOCB Prague, Czech Republic, supervisor: Prof. Josef Michl.

    RESEARCH EXPERIENCE

    • Multi-step syntheses of molecular-level devices.
    • Synthesis of chiral organic cations via organometallic catalysis, non-chromatographic purifications.
    • Optical resolution of chiral organic cations using chiral anions.
    • Growing X-Ray quality crystals.
    • DFT calculations of ground and transition states of molecules.
    • TD-DFT calculations of UV-VIS and ECD spectra.

    AWARDS AND CONFERENCES

    • 2026: Poster contribution in Mach-5 Molecular Machinery: Making Measuring Modelling conference (organized by Jiří Kaleta, Ph.D.) 6-9.9.2026 in Liblice. Light-Gated Control of Brownian Rotation by a Molecular Motor.
    • 2025: Poster contribution in Molecular Rotors, Motors & Switches MoRoMoS2025 (organized by Jiří Kaleta, Ph.D.), IOCB Prague, Czech Republic, 25.-26.9.2025. Coupled Rotation: When a Light-Driven Motor Meets a Molecular Rotor.
    • 2021: Oral contribution in XX Interdisciplinary meeting of young life scientists, on-line, 17.5.-20.5.2021. Regular Arrays of Molecular Switches: Synthesis, Self-Assembly and Characterization. Among five finalists.
    • 2019: Poster contribution in Molecular Rotor Workshop (organized by Jiří Kaleta, Ph.D.), IOCB Prague, Czech Republic, 21.-22.11.2019. Synthesis of Molecular Switches for Self-Assembly on Surfaces.
    • 2015: Poster contribution in the "Liblice 2015" conference, 50th Advances in Organic, Bioorganic and Pharmaceutical Chemistry, Hotel Clarion, Olomouc, 6.-8.11.2015. Dutch Resolution of a Configurationally Stable [5]Helquat with Two Activated Methyl Groups.
    • 2014: Oral contribution in XIV Mezioborové setkání mladých biologů, biochemiků a chemiků conference, hotel Devět skal, Milovy, 13.-16.5.2014. [5]Helquat: Příprava enantiomerů a následná derivatizace.
    • 2013: Poster contribution in the "Liblice 2013" conference, 48th Advances in Organic, Bioorganic and Pharmaceutical Chemistry, Harmony Hotel, Špindelrův Mlýn, 1.-3.11.2013. Gram Scale Resolution of a [5]Helquat.
    • 2012: Oral contribution in the "Liblice 2012" conference, 47th Advances in Organic, Bioorganic and Pharmaceutical Chemistry, Hotel Tree of Life, Lázně Bělohrad, 2.-4.11.2012. Non-racemic Chiral [8]Circulenoid. One of three best presentations.
    • 2012: Oral contribution in XII Mezioborové setkání mladých biologů, biochemiků a chemiků conference, resort Svatá Kateřina, Počátky u Pelhřimova, 29.5.-1.6.2012. [8]Circulenoid: New Chiral Dicationic Circulene-like structure. Among five finalists for the best presentation.
    • 2011: Award of Miloš Hudlický for an important paper published in journals of ChemPubSoc Europe in 2009.
    • 2010: Oral contribution in the "Liblice 2010" conference, Pokroky v organické, bioorganické a farmaceutické chemii, Nymburk, 20.-22.11.2010. Saddlequat: Helquat přistižený na racemizační cestě. 4th best presentation.
    • 2010: Oral contribution in Studentská vědecká konference (SVK), FCHT UCT Prague, 19.11.2010. Saddlequat: DFT výpočet a realita. First prize.
    • 2010: Poster contribution in X Mezioborové setkání mladých biologů, biochemiků a chemiků conference, hotel Devět skal, Milovy, 25.-28.5.2010. Resoluce helquatů na enantiomery: od helquatů k saddlequatu.
    • 2010: Oral contribution in IOCB retreat in Frymburk, May 2010. Saddlequat: A [6]helquat captured on its racemization pathway. One of awarded presentations.
    • 2010: Oral contribution in 7th Supraphone meeting in Maria Laach, Bonn, Germany, April 2010. Synthesis and properties of helquats.
    • 2009: Oral contribution in Studentská vědecká konference (SVK), FCHT UCT Prague, 20.11.2009. Syntéza nesymetrických [7]helquatů. Third prize.
    • 2009: Oral contribution in IX Mezioborové setkání mladých biologů, biochemiků a chemiků, hotel Devět skal, Milovy, 26.-29.5.2009. [7]Helquat: Flexibilní syntéza symetrických a nesymetrických helikálních dikationtů. Among five finalists.
    • 2008: Oral contribution in Studentská vědecká konference (SVK), FCHT VŠCHT Praha, 21.11.2008. [7]HELQUAT: Robustní třísupňová syntéza vysoce helikálních dikationtů. First prize.
    • 2006: Grammar School Scientific Work, Quantum-chemical calculations of properties of some azoniahelicenes, second prize in a National Competition, Special Award of the Learned Society of the Czech Republic for Grammar School Student.
    • 2006: Fifth place in Czech National Chemistry Olympiad.
    • 2006: First place in Regional Physics Olympiad (Středočeský kraj).

    All publications

    Latest publications

    Light-Gated Control of Brownian Rotation by a Molecular Motor
    L. Severa K. Bezděková K. Majerová Varga G. Bastien M. Stroka I. Císařová M. Dračínský J. Kaleta
    Angewandte Chemie International Edition 65 (45): e7061287 (2026)
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    Surface-Decoupled Altitudinal and Azimuthal Triptycene-Fused Tetrapodal Molecular Motors
    K. Bezděková L. Severa E. Kaletová K. Majerová Varga M. Mašát L. Wu J. Jiang I. Císařová J. Kaleta
    Angewandte Chemie International Edition 65 (2): e202513922 (2026)
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    Triptycene-Based Tripodal Molecular Platforms
    G. Bastien L. Severa M. Škuta C. Santos Hurtado J. Rybáček V. Šolínová I. Císařová V. Kašička J. Kaleta
    Chemistry - A European Journal 30 (56): e202401889 (2024)
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    Determination of the binding constants and ionic mobilities of diquat complexes with randomly sulfated cyclodextrins by affinity capillary electrophoresis
    J. Bílek D. Koval V. Šolínová H. R. Talele L. Severa P. E. Reyes Gutierrez F. Teplý V. Kašička
    Journal of Separation Science 47 (11): 2400286 (2024)
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