Jiří Brynda

jiri.brynda@uochb.cas.cz

+420 220 183 210

Scientist

Pavlína Maloy Řezáčová Group

Structural Biology

All publications

Latest publications

Beyond Natural Flavonoids: Exploring Bioisosterism in Design and Synthesis of Influenza Endonuclease Inhibitors

R. Reiberger M. Kráľ K. Radilová T. Kotačka A. Tsalyy P. Majer M. Dračínský J. Brynda J. Konvalinka M. Kožíšek A. Machara

RSC Medicinal Chemistry 16 (7): 3030-3048 (2025)

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On-Resin Assembly of Macrocyclic Inhibitors of Cryptococcus neoformans May1: A Pathway to Potent Antifungal Agents

R. Kryštůfek V. Verner P. Šácha M. Hadzima F. Trajhan J. Starková E. Tloušťová A. Dvořáková A. Pecina J. Brynda J. Chalupský M. Hájek M. J. Boucher P. Majer J. Řezáč H. D. Madhani C. S. Craik J. Konvalinka

Journal of Medicinal Chemistry 68 (9): 9623–9637 (2025)

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Using environment-sensitive tetramethylated thiophene-BODIPY fluorophores in DNA probes for studying effector-induced conformational changes of protein–DNA complexes

M. Šoltysová P. Güixens-Gallardo I. Sieglová A. Soldánová V. Krejčiříková M. Fábry J. Brynda P. Khoroshyy M. Hocek P. Řezáčová

RSC Chemical Biology 6 (3): 376–386 (2025)

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Structural analysis of the stable form of fibroblast growth factor 2 – FGF2-STAB

G. de La Bourdonnaye M. Marek T. Ghazalová J. Damborský P. Pachl J. Brynda V. Štěpánková R. Chaloupková

Journal of Structural Biology: X 10: 100112 (2024)

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Jiří Brynda

Latest publications