Jiří Brynda
Latest publications
The structural basis of aldo-keto reductase 1C3 inhibition by 17α-picolyl and 17(E)-picolinylidene androstane derivatives
Journal of Enzyme Inhibition and Medicinal Chemistry 40 (1): 2551979 (2025)
Affinity and Selectivity of Protein–Ligand Recognition: A Minor Chemical Modification Changes Carbonic Anhydrase Binding Profile
Journal of Medicinal Chemistry 68 (16): 17752–17773 (2025)
Beyond Natural Flavonoids: Exploring Bioisosterism in Design and Synthesis of Influenza Endonuclease Inhibitors
RSC Medicinal Chemistry 16 (7): 3030-3048 (2025)
On-Resin Assembly of Macrocyclic Inhibitors of Cryptococcus neoformans May1: A Pathway to Potent Antifungal Agents
Journal of Medicinal Chemistry 68 (9): 9623–9637 (2025)