Jiří Brynda

All publications

Latest publications

Trapping SARS-CoV-2 main protease into transient artificial zymogens for high-yield expression and simplified purification

P. Novotný A. Moravcová V. Nováková L. Bednárová Z. Voburka J. Brynda R. Souček T. Majerová

International Journal of Biological Macromolecules 349: 150827 (2026)

Steroidal A/B-ring fusion as a strategy for isoform-selective inhibition of human carbonic anhydrases

J. Brynda A. Kiss K. Pospíšilová V. Kapras I. Sieglová B. Slavíková P. Řezáčová E. Kudová

RSC Advances 16 (11): 9743–9755 (2026)

Fat or flat? The impact of dipole moment vectors on non-covalent interactions between aromatic tags and macromolecules

J. Holub A. Jílková C. Lemke L. Cianni P. Spiwoková M. Horn C. Breuer A. Leontovyč J. Brynda H. Mertlíková-Kaiserová M. Chanová F. dos Reis Rocho C. A. Montanari N. El-Sakkary C. R. Caffrey M. Gütschow D. Hnyk M. Mareš J. Fanfrlík

Inorganic Chemistry Frontiers 13 (2): 364–376 (2026)

The structural basis of aldo-keto reductase 1C3 inhibition by 17α-picolyl and 17(E)-picolinylidene androstane derivatives

J. J. Plavša-Puž J. Brynda J. J. Ajduković S. Bekic A. Ćelić P. Řezáčová J. Škerlová E. Petri

Journal of Enzyme Inhibition and Medicinal Chemistry 40 (1): 2551979 (2025)