CS

Jiří Brynda

mail jiri.bryndainvalid-email-name@invalid-email-domainuochb.cas.cz
phone +420 220 183 210
Scientist
Pavlína Maloy Řezáčová Group
Structural Biology
All publications

Latest publications

X-ray structure of human aldo–keto reductase 1C3 in complex with a bile acid fused tetrazole inhibitor: experimental validation, molecular docking and structural analysis
M. A. Marinović S. S. Bekić M. Kugler J. Brynda J. Škerlová D. Đ. Škorić P. Řezáčová E. T. Petri A. S. Ćelić
RSC Medicinal Chemistry 14 (2): 341-355 (2023)
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B-H⋯π and C-H⋯π interactions in protein-ligand complexes: carbonic anhydrase II inhibition by carborane sulfonamides
J. Fanfrlík J. Brynda M. Kugler M. Lepšík K. Pospíšilová J. Holub D. Hnyk J. Nekvinda B. Grüner P. Řezáčová
Physical Chemistry Chemical Physics 25 (3): 1728–1733 (2023)
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Design, Synthesis, and Biochemical and Biological Evaluation of Novel 7-Deazapurine Cyclic Dinucleotide Analogues as STING Receptor Agonists
Z. Vavřina P. Perlíková N. Milisavljevič F. Chevrier M. Smola J. Smith M. Dejmek V. Havlíček M. Buděšínský R. Liboska L. Vaneková J. Brynda E. Bouřa P. Řezáčová M. Hocek G. Birkuš
Journal of Medicinal Chemistry 65 (20): 14082–14103 (2022)
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Highly potent inhibitors of cathepsin K with a differently positioned cyanohydrazide warhead: structural analysis of binding mode to mature and zymogen-like enzymes
J. Benýšek M. Buša P. Rubešová J. Fanfrlík M. Lepšík J. Brynda Z. Matoušková U. Bartz M. Horn M. Gütschow M. Mareš
Journal of Enzyme Inhibition and Medicinal Chemistry 37 (1): 515–526 (2022)
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