Jiří Brynda

All publications

Latest publications

The structural basis of aldo-keto reductase 1C3 inhibition by 17α-picolyl and 17(E)-picolinylidene androstane derivatives

J. J. Plavša-Puž J. Brynda J. J. Ajduković S. Bekic A. Ćelić P. Řezáčová J. Škerlová E. Petri

Journal of Enzyme Inhibition and Medicinal Chemistry 40 (1): 2551979 (2025)

Affinity and Selectivity of Protein–Ligand Recognition: A Minor Chemical Modification Changes Carbonic Anhydrase Binding Profile

A. Zakšauskas V. Paketurytė-Latvė A. Janku̅naitė E. Čapkauskaitė Y. Becart A. Smirnov K. Pospíšilová J. Leitans J. Brynda A. Kazaks L. Baranauskienė E. Manakova S. Gražulis V. Kairys K. Tars P. Řezáčová D. Matulis

Journal of Medicinal Chemistry 68 (16): 17752–17773 (2025)

Beyond Natural Flavonoids: Exploring Bioisosterism in Design and Synthesis of Influenza Endonuclease Inhibitors

R. Reiberger M. Kráľ K. Radilová T. Kotačka A. Tsalyy P. Majer M. Dračínský J. Brynda J. Konvalinka M. Kožíšek A. Machara

RSC Medicinal Chemistry 16 (7): 3030-3048 (2025)

On-Resin Assembly of Macrocyclic Inhibitors of Cryptococcus neoformans May1: A Pathway to Potent Antifungal Agents

R. Kryštůfek V. Verner P. Šácha M. Hadzima F. Trajhan J. Starková E. Tloušťová A. Dvořáková A. Pecina J. Brynda J. Chalupský M. Hájek M. J. Boucher P. Majer J. Řezáč H. D. Madhani C. S. Craik J. Konvalinka

Journal of Medicinal Chemistry 68 (9): 9623–9637 (2025)