Jiří Brynda

jiri.brynda@uochb.cas.cz

+420 220 183 210

Scientist

Pavlína Maloy Řezáčová Group

Structural Biology

All publications

Latest publications

Crystal structure of blue laccase BP76, a unique termite suicidal defense weapon

J. Škerlová J. Brynda J. Šobotník M. Zákopčaník P. Novák T. Bourguignon D. Sillam-Dussès P. Řezáčová

Structure 32 (10): 1581-1585.e5 (2024)

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Nature-Inspired Gallinamides Are Potent Antischistosomal Agents: Inhibition of the Cathepsin B1 Protease Target and Binding Mode Analysis

P. Spiwoková M. Horn J. Fanfrlík A. Jílková P. Fajtová A. Leontovyč A. Houštecká L. Bieliková J. Brynda M. Chanová H. Mertlíková-Kaiserová E. J. E. Caro-Diaz J. Almaliti N. El-Sakkary W. H. Gerwick C. R. Caffrey M. Mareš

ACS Infectious Diseases 10 (6): 1935–1948 (2024)

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Design, Synthesis, Biological Evaluation, and Crystallographic Study of Novel Purine Nucleoside Phosphorylase Inhibitors

J. Skácel S. Đukić O. Baszczyňski F. Kalčic T. Bílek K. Chalupský J. Kozák A. Dvořáková E. Tloušťová Z. Kráľová M. Šmídková J. Voldřich M. Rumlová P. Pachl J. Brynda T. Vučková M. Fábry J. Snášel I. Pichová P. Řezáčová H. Mertlíková-Kaiserová Z. Janeba

Journal of Medicinal Chemistry 66 (10): 6652–6681 (2023)

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X-ray structure of human aldo–keto reductase 1C3 in complex with a bile acid fused tetrazole inhibitor: experimental validation, molecular docking and structural analysis

M. A. Marinović S. S. Bekić M. Kugler J. Brynda J. Škerlová D. Đ. Škorić P. Řezáčová E. T. Petri A. S. Ćelić

RSC Medicinal Chemistry 14 (2): 341–355 (2023)

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Jiří Brynda

Latest publications