Profile

Research Interests

Ooganic synthesis and catalysis, organometallic chemistry, stereochemistry & chirality, π-electron & aromatic systems, self-assembly, on-surface chemistry, nanoparticles, molecular electronics and single-molecule devices

Education

1993-1994

Postdoctoral fellow with Prof. E. P. Kündig, Université de Genève, Switzerland

1990

Ph.D. (CSc.) in Organic Chemistry, Czechoslovak Academy of Sciences, under supervision of Prof. P. Kočovský at the Institute of Organic Chemistry and Biochemistry, Czechoslovak Academy of Sciences, Prague

1984

M.Sc. (RNDr.) in Bioorganic Chemistry, Charles University, Prague, under supervision of Prof. P. Kočovský at the Institute of Organic Chemistry and Biochemistry, Czechoslovak Academy of Sciences, Prague

Chronology of Employment

Since 2007

Head of the Senior Research Group, Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Prague

2003-2006

Head of the Department of Organic Chemistry, Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Prague

2000-2006

Research Group Leader (Organic Synthesis) at the Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Prague

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Research Sabbaticals

2000-2001

Research assistant with Prof. P. Kočovský, University of Glasgow, United Kingdom

Honors & Scientific Recognition

2018

Rudolf Lukeš Award (Czech Chemical Society)

Since 2017

Elected member of The Learned Society of the Czech Republic, member of the Executive Board

2016

IOCF Yoshida Lectureship 

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Publications

90 original papers, 4 chapters in books / h-index: 31

Selected papers

An Ultimate Stereocontrol in Asymmetric Synthesis of Optically Pure Fully Aromatic Helicenes
An Ultimate Stereocontrol in Asymmetric Synthesis of Optically Pure Fully Aromatic Helicenes
Journal of the American Chemical Society 137 (26): 8469-8474 (2015)
The role of the helicity of small molecules in enantioselective \ncatalysis, molecular recognition, self-assembly, material science, \nbiology, and nanoscience is much less understood than that of point-, \naxial-, or planar-chiral molecules. To uncover the envisaged potential \nof helically chiral polyaromatics represented by iconic helicenes, their\n availability in an optically pure form through asymmetric synthesis is \nurgently needed. We provide a solution to this problem present since the\n birth of helicene chemistry in 1956 by developing a general synthetic \nmethodology for the preparation of uniformly enantiopure fully aromatic \n[5]-, [6]-, and [7]helicenes and their functionalized derivatives. [2 + 2\n + 2] Cycloisomerization of chiral triynes combined with asymmetric \ntransformation of the first kind (ultimately controlled by the \n1,3-allylic-type strain) is central to this endeavor. The \npoint-to-helical chirality transfer utilizing a traceless chiral \nauxiliary…

Latest publications

Towards dielectric relaxation at a single molecule scale
Scientific Reports 12: 2865 (2022)
Nonaqueous capillary electrophoresis and quantum chemical calculations applied to investigation of acid–base and electromigration properties of azahelicenes
Electrophoresis 43 (5-6): 696-707 (2022)
Synthesis of (Di)thiahelicenes and Dithiophenohelicenes by [2+2+2] Cycloisomerization of Alkynes
Helvetica Chimica Acta 105 (3): e202100225 (2022)
On‐Surface Synthesis of Polyferrocenylene and its Single‐Chain Conformational and Electrical Transport Properties
Advanced Functional Materials 31 (5): 2006391 (2021)