Ivo Starý, Ph.D.
+420 731 447 870
+420 220 183 315
Vybrané publikace
An Ultimate Stereocontrol in Asymmetric Synthesis of Optically Pure Fully Aromatic Helicenes
Journal of the American Chemical Society 137 (26): 8469-8474 (2015)
The role of the helicity of small molecules in enantioselective \ncatalysis, molecular recognition, self-assembly, material science, \nbiology, and nanoscience is much less understood than that of point-, \naxial-, or planar-chiral molecules. To uncover the envisaged potential \nof helically chiral polyaromatics represented by iconic helicenes, their\n availability in an optically pure form through asymmetric synthesis is \nurgently needed. We provide a solution to this problem present since the\n birth of helicene chemistry in 1956 by developing a general synthetic \nmethodology for the preparation of uniformly enantiopure fully aromatic \n[5]-, [6]-, and [7]helicenes and their functionalized derivatives. [2 + 2\n + 2] Cycloisomerization of chiral triynes combined with asymmetric \ntransformation of the first kind (ultimately controlled by the \n1,3-allylic-type strain) is central to this endeavor. The \npoint-to-helical chirality transfer utilizing a traceless chiral \nauxiliary…
Nejnovější publikace
Helicene-based π-conjugated macrocycles: their synthesis, properties, chirality and self-assembly into molecular stripes on a graphite surface
Nanoscale 15 (4): 1542–1553 (2023)
Electrochemistry of Tetrathiafulvalene Ligands Assembled on the Surface of Gold Nanoparticles
Molecules 27 (21): 7639 (2022)
Push–pull amino-nitro helicenes: synthesis, (chir)optical properties and self-assembly into thin films
Chemical Communications 58 (91): 12732–12735 (2022)
Cycloiridated Helicenes as Chiral Catalysts in the Asymmetric Transfer Hydrogenation of Imines
ACS Catalysis 12 (17): 10793–10800 (2022)