Aleš Machara, Ph.D.

All publications

Latest publications

Targeting NFE2L1 signalling with small molecules to protect against Ferroptosis

L. Svobodová J. Sedláček Z. Šmahelová P. Majer A. Machara K. Grantz Šašková

Bioorganic and Medicinal Chemistry Letters 130: 130425 (2026)

Investigating NFE2L1 activators for targeted protein aggregate clearance: a follow-up study

Z. Šmahelová L. Svobodová J. Sedláček M. Adámek M. Pimková Polidarová P. Majer A. Machara K. Grantz Šašková

RSC Medicinal Chemistry 16 (12): 6397–6411 (2025)

Identification of the trail-following pheromone receptor in termites

S. Diallo K. Kašparová J. Šulc J. Johny J. Křivánek J. Nebesářová D. Sillam-Dussès P. Kyjaková J. Vondrášek A. Machara O. Lukšan E. Grosse-Wilde R. Hanus

eLife 13: RP101814 (2025)

Beyond Natural Flavonoids: Exploring Bioisosterism in Design and Synthesis of Influenza Endonuclease Inhibitors

R. Reiberger M. Kráľ K. Radilová T. Kotačka A. Tsalyy P. Majer M. Dračínský J. Brynda J. Konvalinka M. Kožíšek A. Machara

RSC Medicinal Chemistry 16 (7): 3030-3048 (2025)