CS
Dr. Jindřich Nejedlý

Dr. Jindřich Nejedlý

mail jindrich.nejedlyinvalid-email-name@invalid-email-domainuochb.cas.cz
phone +420 220 183 226
Postdoctoral fellow
Ivo Starý Group
Chemistry of Functional Molecules

Profile

Research Interests

Organic Synthesis, Single-Molecule Conductance Measurement

Education

2021

Ph.D. in Organic Chemistry at the Faculty of Natural Sciences, Charles University, Prague, under supervision of Dr. Ivo Starý at the Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Prague

2012

M.Sc. in Organic Chemistry at the Faculty of Natural Sciences, Charles University, Prague, under supervision of Dr. Ivo Starý at the Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Prague

2010

Bc. in Organic Chemistry at the Faculty of Natural Sciences, Charles University, Prague, under supervision of Dr. Ivo Starý at the Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Prague

Chronology of Employment

since 2009

Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Prague, Dr. Ivo Starý group, current position: Postdoctoral Fellow

All publications

Selected papers

Synthesis of Long Oxahelicenes by Polycyclization in a Flow Reactor
Synthesis of Long Oxahelicenes by Polycyclization in a Flow Reactor
J. Nejedlý M. Šámal J. Rybáček M. Tobrmanová F. Szydlo C. Coudret J. Vacek J. Vacek Chocholoušová M. Buděšínský D. Šaman L. Bednárová L. Sieger I. G. Stará I. Starý
Angewandte Chemie International Edition 56 (21): 5839-5843 (2017)
A series of oxahelicenes composed of ortho/meta‐annulated benzene/pyridine and 2H‐pyran rings were synthesized on the basis of the cobalt(I)‐mediated (or rhodium(I)‐ or nickel(0)‐mediated) double, triple, or quadruple [2+2+2] cycloisomerization of branched aromatic hexa‐, nona‐, or dodecaynes, thus allowing the construction of 6, 9, or 12 rings in a single operation. The use of a flow reactor was found to be beneficial for the multicyclization reactions. The stereogenic centers present in some of the oligoynes steered the helical folding in such a way that the final oxa[9]‐, [13]‐, [17]‐ and [19]helicenes were obtained in both enantiomerically and diastereomerically pure form. Specifically, the oxa[19]helicenes beat the current record in the length of a helicene backbone. Single‐molecule conductivity was studied by the mechanically controllable break‐junction method with a pyridooxa[9]helicene.
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All publications

Latest publications

Towards dielectric relaxation at a single molecule scale
V. Stetsovych S. Feigl R. Vranik B. Wit E. Rauls J. Nejedlý M. Šámal I. Starý S. Müllegger
Scientific Reports 12: 2865 (2022)
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Synthesis of (Di)thiahelicenes and Dithiophenohelicenes by [2+2+2] Cycloisomerization of Alkynes
O. Palata A. Andronova M. Šámal J. Nejedlý J. Rybáček M. Buděšínský L. Bednárová L. Pospíšil I. Císařová I. Starý I. G. Stará
Helvetica Chimica Acta 105 (3): e202100225 (2022)
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Synthesis of Racemic, Diastereopure, and Enantiopure Carba- or Oxa[5]-, [6]-, [7]-, and -[19]helicene (Di)thiol Derivatives
J. Nejedlý M. Šámal J. Rybáček I. Gay Sánchez V. Houska T. Warzecha J. Vacek L. Sieger M. Buděšínský L. Bednárová P. Fiedler I. Císařová I. Starý I. G. Stará
Journal of Organic Chemistry 85 (1): 248-276 (2020)
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Large Converse Piezoelectric Effect Measured on a Single Molecule on a Metallic Surface
O. Stetsovych P. Mutombo M. Švec M. Šámal J. Nejedlý I. Císařová H. Vázquez M. Moro-Lagares J. Berger J. Vacek I. G. Stará I. Starý P. Jelínek
Journal of the American Chemical Society 140 (3): 940-946 (2018)
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