Profil

Oblasti zájmu

organická syntéza, měření vodivosti molekul

Vzdělání

2021

Ph.D. v oboru organické chemie, Přírodovědecká fakulta, Univerzita Karlova v Praze, pod vedením RNDr. Iva Starého, CSc. na Ústavu organické chemie a biochemie Akademie věd České republiky, Praha

2012

Magistr organické chemie, Přírodovědecká fakulta, Univerzita Karlova v Praze, pod vedením RNDr. Iva Starého, CSc. na Ústavu organické chemie a biochemie Akademie věd České republiky, Praha

2010

Bakalář organické chemie, Přírodovědecká fakulta, Univerzita Karlova v Praze, pod vedením RNDr. Iva Starého, CSc. na Ústavu organické chemie a biochemie Akademie věd České republiky, Praha

Zaměstnání

od 2009

Ústav organické chemie a biochemie Akademie věd České republiky, v.v.i., Praha, skupina RNDr. Iva Starého, CSc., aktuální pozice: postdoktorand



Vybrané publikace

Synthesis of Long Oxahelicenes by Polycyclization in a Flow Reactor
Synthesis of Long Oxahelicenes by Polycyclization in a Flow Reactor
Angewandte Chemie International Edition 56 (21): 5839-5843 (2017)
A series of oxahelicenes composed of ortho/meta‐annulated benzene/pyridine and 2H‐pyran rings were synthesized on the basis of the cobalt(I)‐mediated (or rhodium(I)‐ or nickel(0)‐mediated) double, triple, or quadruple [2+2+2] cycloisomerization of branched aromatic hexa‐, nona‐, or dodecaynes, thus allowing the construction of 6, 9, or 12 rings in a single operation. The use of a flow reactor was found to be beneficial for the multicyclization reactions. The stereogenic centers present in some of the oligoynes steered the helical folding in such a way that the final oxa[9]‐, [13]‐, [17]‐ and [19]helicenes were obtained in both enantiomerically and diastereomerically pure form. Specifically, the oxa[19]helicenes beat the current record in the length of a helicene backbone. Single‐molecule conductivity was studied by the mechanically controllable break‐junction method with a pyridooxa[9]helicene.

Nejnovější publikace

Synthesis of Racemic, Diastereopure, and Enantiopure Carba- or Oxa[5]-, [6]-, [7]-, and -[19]helicene (Di)thiol Derivatives
Journal of Organic Chemistry 85 (1): 248-276 (2020)
Large Converse Piezoelectric Effect Measured on a Single Molecule on a Metallic Surface
Journal of the American Chemical Society 140 (3): 940-946 (2018)
Oxahelicene NHC ligands in the asymmetric synthesis of nonracemic helicenes
Chemical Communications 53 (31): 4370-4373 (2017)