Pavel Majer

pavel.majer@uochb.cas.cz

+420 220 183 125

Group leader

Pavel Majer Group

Drug Discovery

All publications

Latest publications

Discovery of Orally Available Prodrugs of Itaconate and Derivatives

C. B. Lee I. Šnajdr L. Tenora J. Alt S. Gori M. Krečmerová R. M. Maragakis J. Paule S. Tiwari J. Iyer R. Talwar L. Garza P. Majer B. S. Slusher R. Rais

Journal of Medicinal Chemistry 68 (3): 3433–3444 (2025)

Go to the publication

3′-Dehydroxypurpurogallin-4-Carboxamides as Influenza A Endonuclease Inhibitors: Synthesis, Structure-Activity Relationship Analysis, and Structural Characterization of Protein Complex

M. Kráľ T. Kotačka R. Reiberger G. Panýrková K. Radilová Z. Osifová M. Flieger J. Konvalinka P. Majer M. Kožíšek A. Machara

ChemMedChem 20 (3): e202400577 (2025)

Go to the publication

The evaluation of DNA-linked inhibitor antibody and AlphaScreen assays for high-throughput screening of compounds targeting the cap-binding domain in influenza a polymerase

K. Čermáková J. Gregor M. Kráľ E. Karlukova V. Navrátil R. Reiberger C. Berenguer Albinana V. Bechynský P. Majer J. Konvalinka A. Machara M. Kožíšek

European Journal of Pharmaceutical Sciences 205: 106990 (2025)

Go to the publication

Small-molecule activators of NRF1 transcriptional activity prevent protein aggregation

J. Sedláček Z. Šmahelová M. Adámek D. Šubová L. Svobodová A. Kadlecová P. Majer A. Machara K. Grantz Šašková

Biomedicine & Pharmacotherapy 183: 117864 (2025)

Go to the publication

${ item.category }

Pavel Majer

Latest publications