SCIEX QTRAP 6500+

  • Large MS Instruments
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The SCIEX QTRAP 6500+ system combines triple quadrupole mass spectrometry with linear ion trap (LIT). The system consists of serially connected three quadrupoles with a potential of using the last one as LIT for improved MS scans, such as Enhanced MS (EMS), Enhanced Multi-Charge (EMC), Enhanced Product Ion (EPI), Enhanced Resolution (ER) and MS/MS/MS (MS3). The QTRAP 6500+ system connects with ExionLC UHPLC system through atmospheric pressure ion sources – ESI or APCI. The QTRAP 6500+ system also offers connection of an optional module – differential mobility spectrometry (DMS, SelexION technology) thus allowing separation of isobaric species based on their collision cross section.

At the research-service team of Mass Spectrometry, the QTRAP system is used for quantification in general and targeted metabolomics studies. Such setup enables separation and targeted quantification of small molecules, e.g., neurotransmitters, nucleosides/nucleotides, phytoprostanes, especially when using multiple reaction monitoring mode (MRM).

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