List of PhD projects in 2024

CHEM cluster

Development of new organic reagents for consecutive orthogonal click reactions and their application (Petr Beier Group)
Sequence-specific enzymatic synthesis of base-modified RNA (Michal Hocek Group)
Modified nucleotides for selection of functional nucleic acids and labelled probes for chemical biology (Michal Hocek Group)
New cytostatic nucleosides and nucleotides with new mechanisms of action (Michal Hocek Group)
Multiphotochromic molecular machines (Jiří Kaleta Group)
Synthesis of low-molecular compounds for specific targeting of important therapeutic targets (Jan Konvalinka Group)
Catalytic stereoselective synthesis of elusive atropisomers for drug discovery (Paulo Paioti Group)
Photochemistry and spectroscopy of organic radical ions (Tomáš Slanina Group)

Development of methods to study 5’ RNA structure and sequence (Hana Cahová Group)
The polymeric conjugates as an experimental tool in immunomodulation and immunotherapy (Jan Konvalinka Group)
Viral proteases of important human pathogens (Jan Konvalinka Group)
Structural studies of histone chaperones (Pavlína Maloy Řezáčová Group)
Regulation of growth and metabolism (David Sabatini Group)
Cryo-EM structural biology of diseases: Rationally designed viral-RNA based inhibitors of influenza RNA polymerase (Cryogenic Electron Microscopy)

Development of a methodology for protein analysis by native CE-MS (Electromigration Methods)