List of PhD projects in 2025
CHEM cluster
- Quantum sensing using optical bionanosensors (Petr Cígler Group)
- Preparation and characterization of quantum-optical bionanosensors (Petr Cígler Group)
- Chemoenzymatic syntheses of modified tRNAs (Michal Hocek Group)
- Enzymatic synthesis of modified oligonucleotides and DNA bearing several modifications at specific positions (Michal Hocek Group)
- Selection of hydrophobic aptamers targeting steroids (Michal Hocek Group)
- Hypermodified SELEX using combination of three or four modified nucleotides (Michal Hocek Group)
- Multiphotochromic molecular machines (Jiří Kaleta Group)
- Inhibitors of methyltransferases – design and synthesis of potential new drugs (Radim Nencka Group)
- Catalytic synthesis of atropisomers by substitution (Paulo Paioti Group)
- Study of photochemistry of non-classical electrophiles and Lewis acids (Tomáš Slanina Group)
- Development of reversible photoinduced electron transfer (Tomáš Slanina Group)
- Warped and chiral nanocarbons (Ivo Starý Group)
- Synthesis and chiroptical properties of helicene-derived luminophores (Ivo Starý Group)
- Helically chiral ligands for asymmetric transition metal catalysis (Ivo Starý Group)
BIO cluster
- Development of methods to study 5’ RNA termini structure and sequence (Hana Cahová Group)
- Bioinformatic analysis of catalytic DNA molecules (Edward Curtis Group)
- Proteases of human viruses: properties, maturation, inhibition (Jan Konvalinka Group)
- Investigating replication mechanisms and inhibitor resistance in bunyaviruses: focus on Rift Valley fever virus (RVFV) and Hazara virus (Jan Konvalinka Group)
- Targeting the brain: blood-to-brain transport of lipidized neuropeptides, potential therapeutics (Lenka Maletínská Group)
- Computational mass spectrometry (Tomáš Pluskal Group)
- Structural analysis of small molecules using crystalline sponge X-ray diffraction (Tomáš Pluskal Group)
- Metabolic engineering for bioproduction of terpenoids (Tomáš Pluskal Group)
- Discovery of unique chemical structures of plant metabolites (Tomáš Pluskal Group)
- Regulation of growth and metabolism by the mTOR pathway (David Sabatini Group)
- Understanding the specificity of intramembrane proteases using biophysical principles and artificial intelligence (Kvido Stříšovský Group)
PHYS cluster
- Computational modeling of molecular spectroscopic properties (Petr Bouř Group)
- Ab initio prediction of protein 3-D structures as a road to 'Terra Incognita' of their conformational landscapes (Lubomír Rulíšek Group)
- Development of neural network force fields (NNFFs) for exploration of enzymatic chemical reactions (Lubomír Rulíšek Group)
- Spinristor and memristor: molecular switches with added functions (Lubomír Rulíšek Group)