Dominika Chalupská

Všechny publikace

Nejnovější publikace

Structural mechanism and inhibitor discovery for DhhP, a Borrelia burgdorferi cyclic di-AMP phosphodiesterase with an Fe/Mn bimetallic center

M. Klíma M. Dejmek A. Palusová D. Chalupská P. Pachl A. Hušková J. Hraníček K. Chalupský M. Moos R. Nencka J. Perner E. Bouřa

Structure 2026: Early View

Discovery of highly potent SARS-CoV-2 nsp14 methyltransferase inhibitors based on adenosine 5′-carboxamides

H. Kocek D. Chalupská A. Dvořáková M. Zgarbová M. Šála K. Chalupský P. Krafčíková T. Otava M. Drexler E. Procházková B. Klepetářová M. Štefek J. Kozic H. Mertlíková-Kaiserová E. Bouřa J. Weber R. Nencka

RSC Medicinal Chemistry 15 (10): 3469-3476 (2024)

Structural and functional insights in flavivirus NS5 proteins gained by the structure of Ntaya virus polymerase and methyltransferase

K. Krejčová P. Krafčíková M. Klíma D. Chalupská K. Chalupský E. Žilecká E. Bouřa

Structure 32 (8): 1099-1109.e3 (2024)

Fluorinated cGAMP analogs, which act as STING agonists and are not cleavable by poxins: Structural basis of their function

M. Klíma M. Dejmek V. Duchoslav A. Eisenreichová M. Šála K. Chalupský D. Chalupská B. Novotná G. Birkuš R. Nencka E. Bouřa

Structure 32 (4): 433–439.e4 (2024)