Dominika Chalupská

Všechny publikace

Nejnovější publikace

Discovery of highly potent SARS-CoV-2 nsp14 methyltransferase inhibitors based on adenosine 5′-carboxamides

H. Kocek D. Chalupská A. Dvořáková M. Zgarbová M. Šála K. Chalupský P. Krafčíková T. Otava M. Drexler E. Procházková B. Klepetářová M. Štefek J. Kozic H. Mertlíková-Kaiserová E. Bouřa J. Weber R. Nencka

RSC Medicinal Chemistry 15 (10): 3469-3476 (2024)

Structural and functional insights in flavivirus NS5 proteins gained by the structure of Ntaya virus polymerase and methyltransferase

K. Krejčová P. Krafčíková M. Klíma D. Chalupská K. Chalupský E. Žilecká E. Bouřa

Structure 32 (8): 1099-1109.e3 (2024)

Fluorinated cGAMP analogs, which act as STING agonists and are not cleavable by poxins: Structural basis of their function

M. Klíma M. Dejmek V. Duchoslav A. Eisenreichová M. Šála K. Chalupský D. Chalupská B. Novotná G. Birkuš R. Nencka E. Bouřa

Structure 32 (4): 433–439.e4 (2024)

Design, synthesis and evaluation of novel thieno[2,3d]pyrimidine derivatives as potent and specific RIPK2 inhibitors

M. Misehe M. Šála M. Matoušová K. Hercík H. Kocek D. Chalupská E. Chaloupecká M. Hájek E. Bouřa H. Mertlíková Kaiserová R. Nencka

Bioorganic and Medicinal Chemistry Letters 97: 129567 (2024)